SAMe (S-adenosyl methionine) is a replication of a compound that the body produces from the amino acid methionine and occurs naturally in foods such as fish and meat. It is synthesized in the body and was recently made available as a supplement. SAMe appears to raise levels of dopamine, a neurotransmitter important in mood regulation. Thus it can be an effective antidepressant, but it shouldn’t be used by those with bipolar conditions without first consulting a health professional.
